Kronologisk publiceringslista

2019

Occupational exposure to organic dusts and risk of developing rheumatoid arthritis: findings from a Swedish population-based case-control study.

Ilar A, Gustavsson P, Wiebert P, Alfredsson L.

RMD Open. 2019 Nov 21;5(2):e001049. doi: 10.1136/rmdopen-2019-001049. eCollection 2019.

Complex Relationships of Smoking, HLA-DRB1 Genes, and Serologic Profiles in Patients With Early Rheumatoid Arthritis: Update From a Swedish Population-Based Case-Control Study.

Hedström AK, Rönnelid J, Klareskog L, Alfredsson L.

Arthritis Rheumatol. 2019 Sep;71(9):1504-1511. doi: 10.1002/art.40852. Epub 2019 Jul 24.

Distinct HLA Associations with Rheumatoid Arthritis Subsets Defined by Serological Subphenotype.

Terao C, Brynedal B, Chen Z, Jiang X, Westerlind H, Hansson M, Jakobsson PJ, Lundberg K, Skriner K, Serre G, Rönnelid J, Mathsson-Alm L, Brink M, Dahlqvist SR, Padyukov L, Gregersen PK, Barton A, Alfredsson L, Klareskog L, Raychaudhuri S.

Am J Hum Genet. 2019 Sep 5;105(3):616-624. doi: 10.1016/j.ajhg.2019.08.002. Epub 2019 Aug 29. Erratum in: Am J Hum Genet. 2019 Oct 3;105(4):880.

Occupational exposure to asbestos and silica and risk of developing rheumatoid arthritis: findings from a Swedish population-based case-control study.

Ilar A, Klareskog L, Saevarsdottir S, Wiebert P, Askling J, Gustavsson P, Alfredsson L.

RMD Open. 2019 Jul 11;5(2):e000978. doi: 10.1136/rmdopen-2019-000978. eCollection 2019.

Interplay between alcohol, smoking and HLA genes in RA aetiology.

Hedström AK, Hössjer O, Klareskog L, Alfredsson L.

RMD Open. 2019 May 9;5(1):e000893. doi: 10.1136/rmdopen-2019-000893. eCollection 2019.

Interplay between obesity and smoking with regard to RA risk.

Hedström AK, Klareskog L, Alfredsson L.

RMD Open. 2019 Apr 16;5(1):e000856. doi: 10.1136/rmdopen-2018-000856. eCollection 2019.

2018

Mediterranean diet and risk of rheumatoid arthritis: a population-based case-control study.

Johansson K, Askling J, Alfredsson L, Di Giuseppe D; EIRA study group.

Arthritis Res Ther. 2018 Aug 9;20(1):175. doi: 10.1186/s13075-018-1680-2.

Systematic approach demonstrates enrichment of multiple interactions between non-HLA risk variants and HLA-DRB1 risk alleles in rheumatoid arthritis.

Diaz-Gallo LM, Ramsköld D, Shchetynsky K, Folkersen L, Chemin K, Brynedal B, Uebe S, Okada Y, Alfredsson L, Klareskog L, Padyukov L.

Ann Rheum Dis. 2018 Oct;77(10):1454-1462. doi: 10.1136/annrheumdis-2018-213412. Epub 2018 Jul 2.

Exposure to passive smoking and rheumatoid arthritis risk: results from the Swedish EIRA study.

Hedström AK, Klareskog L, Alfredsson L.

Ann Rheum Dis. 2018 Jul;77(7):970-972. doi: 10.1136/annrheumdis-2018-212973. Epub 2018 May 3.

Smoking and susceptibility to rheumatoid arthritis in a Swedish population-based case-control study.

Hedström AK, Stawiarz L, Klareskog L, Alfredsson L.

Eur J Epidemiol. 2018 Apr;33(4):415-423. doi: 10.1007/s10654-018-0360-5. Epub 2018 Jan 31.

2017

Anticitrullinated protein/peptide antibody multiplexing defines an extended group of ACPA-positive rheumatoid arthritis patients with distinct genetic and environmental determinants.

Rönnelid J, Hansson M, Mathsson-Alm L, Cornillet M, Reed E, Jakobsson PJ, Alfredsson L, Holmdahl R, Skriner K, Serre G, Lundberg K, Klareskog L.

Ann Rheum Dis. 2017 Oct 25. pii: annrheumdis-2017-211782. doi: 10.1136/annrheumdis-2017-211782. [Epub ahead of print]

Seropositivity combined with smoking is associated with increased prevalence of periodontitis in patients with rheumatoid arthritis.

Eriksson K, Nise L, Alfredsson L, Catrina AI, Askling J, Lundberg K, Klareskog L, Yucel-Lindberg T.

Ann Rheum Dis. 2017 Oct 6. pii: annrheumdis-2017-212091. doi: 10.1136/annrheumdis-2017-212091. [Epub ahead of print]

Airborne Occupational Exposures and Risk of Developing Rheumatoid Arthritis: A Job-Exposure Matrix Approach in a Swedish Population-Based Case-Control Study.

Ilar A, Alfredsson L, Wiebert P, Klareskog L, Bengtsson C.

Arthritis Care Res (Hoboken). 2017 Oct 3. doi: 10.1002/acr.23436. [Epub ahead of print]

Low levels of antibodies against common viruses associate with anti-citrullinated protein antibody-positive rheumatoid arthritis; implications for disease aetiology.

Sherina N, Hreggvidsdottir HS, Bengtsson C, Hansson M, Israelsson L, Alfredsson L, Lundberg K.

Arthritis Res Ther. 2017 Sep 30;19(1):219. doi: 10.1186/s13075-017-1423-9.

Amount of smoking, duration of smoking cessation and their interaction with silica exposure in the risk of rheumatoid arthritis among males: results from the Swedish Epidemiological Investigation of Rheumatoid Arthritis (EIRA) study.

Zeng P, Chen Z, Klareskog L, Alfredsson L, Bengtsson C, Jiang X.

Ann Rheum Dis. 2017 Sep 15. pii: annrheumdis-2017-212145. doi: 10.1136/annrheumdis-2017-212145. [Epub ahead of print] No abstract available.

Relationship between shift work and the onset of rheumatoid arthritis.

Hedström AK, Åkerstedt T, Klareskog L, Alfredsson L.

RMD Open. 2017 Aug 29;3(2):e000475. doi: 10.1136/rmdopen-2017-000475. eCollection 2017.

Working in cold environment and risk of developing rheumatoid arthritis: results from the Swedish EIRA case-control study.

Zeng P, Bengtsson C, Klareskog L, Alfredsson L.

RMD Open. 2017 Aug 16;3(2):e000488. doi: 10.1136/rmdopen-2017-000488. eCollection 2017.

Oral contraceptives, breastfeeding and the risk of developing rheumatoid arthritis: results from the Swedish EIRA study.

Orellana C, Saevarsdottir S, Klareskog L, Karlson EW, Alfredsson L, Bengtsson C.

Ann Rheum Dis. 2017 Nov;76(11):1845-1852. doi: 10.1136/annrheumdis-2017-211620. Epub 2017 Aug 17.

Occupation and Risk of Developing Rheumatoid Arthritis: Results From a Population-Based Case-Control Study.

Ilar A, Alfredsson L, Wiebert P, Klareskog L, Bengtsson C.

Arthritis Care Res (Hoboken). 2017 Aug 10. doi: 10.1002/acr.23321. [Epub ahead of print]

Are dietary vitamin D, omega-3 fatty acids and folate associated with treatment results in patients with early rheumatoid arthritis? Data from a Swedish population-based prospective study.

Lourdudoss C, Wolk A, Nise L, Alfredsson L, Vollenhoven RV.

BMJ Open. 2017 Jun 10;7(6):e016154. doi: 10.1136/bmjopen-2017-016154.

VAV1 regulates experimental autoimmune arthritis and is associated with anti-CCP negative rheumatoid arthritis.

Guerreiro-Cacais AO, Norin U, Gyllenberg A, Berglund R, Beyeen AD; Rheumatoid Arthritis Consortium International (RACI), Petit-Teixeira E, Cornélis F, Saoudi A, Fournié GJ, Holmdahl R, Alfredsson L, Klareskog L, Jagodic M, Olsson T, Kockum I, Padyukov L.

Genes Immun. 2017 Mar;18(2):109. doi: 10.1038/gene.2017.7. No abstract available.

Physical workload is associated with increased risk of rheumatoid arthritis: results from a Swedish population-based case-control study.

Zeng P, Klareskog L, Alfredsson L, Bengtsson C.

RMD Open. 2017 Mar 14;3(1):e000324. doi: 10.1136/rmdopen-2016-000324. eCollection 2017.

Anticollagen type II antibodies are associated with an acute onset rheumatoid arthritis phenotype and prognosticate lower degree of inflammation during 5 years follow-up.

Manivel VA, Mullazehi M, Padyukov L, Westerlind H, Klareskog L, Alfredsson L, Saevarsdottir S, Rönnelid J.

Ann Rheum Dis. 2017 Mar 23. pii: annrheumdis-2016-210873. doi: 10.1136/annrheumdis-2016-210873. [Epub ahead of print]

DNA methylation mediates genotype and smoking interaction in the development of anti-citrullinated peptide antibody-positive rheumatoid arthritis.

Meng W, Zhu Z, Jiang X, Too CL, Uebe S, Jagodic M, Kockum I, Murad S, Ferrucci L, Alfredsson L, Zou H, Klareskog L, Feinberg AP, Ekström TJ, Padyukov L, Liu Y.

Arthritis Res Ther. 2017 Mar 29;19(1):71. doi: 10.1186/s13075-017-1276-2.

Dietary Intake of Polyunsaturated Fatty Acids and Pain in spite of Inflammatory Control among Methotrexate Treated Early Rheumatoid Arthritis Patients.

Lourdudoss C, Di Giuseppe D, Wolk A, Westerlind H, Klareskog L, Alfredsson L, van Vollenhoven RF, Lampa J.

Arthritis Care Res (Hoboken). 2017 Mar 28. doi: 10.1002/acr.23245. [Epub ahead of print]

2016

A genetic risk score composed of rheumatoid arthritis risk alleles, HLA-DRB1 haplotypes, and response to TNFi therapy - results from a Swedish cohort study.

Jiang X, Askling J, Saevarsdottir S, Padyukov L, Alfredsson L, Viatte S, Frisell T.

Arthritis Res Ther. 2016 Dec 3;18(1):288

Differences in the Spectrum of Anti-Citrullinated Protein Antibody Fine Specificities Between Malaysian and Swedish Patients With Rheumatoid Arthritis: Implications for Disease Pathogenesis.

Too CL, Murad S, Hansson M, Alm LM, Dhaliwal JS, Holmdahl R, Jakobsson PJ, Alfredsson L, Klareskog L, Rönnelid J, Padyukov L.

Arthritis Rheumatol. 2016 Aug 2. doi: 10.1002/art.39827. [Epub ahead of print]

Remaining Pain in Early Rheumatoid Arthritis Patients Treated With Methotrexate.

Altawil R, Saevarsdottir S, Wedrén S, Alfredsson L, Klareskog L, Lampa J.

Arthritis Care Res (Hoboken). 2016 Aug;68(8):1061-8. doi: 10.1002/acr.22790

Prevalence of Periodontitis in Patients with Established Rheumatoid Arthritis: A Swedish Population Based Case-Control Study.

Eriksson K, Nise L, Kats A, Luttropp E, Catrina AI, Askling J, Jansson L, Alfredsson L, Klareskog L, Lundberg K, Yucel-Lindberg T.

PLoS One. 2016 May 20;11(5):e0155956. doi: 10.1371/journal.pone.0155956. eCollection 2016.

Antibodies to carbamylated α-enolase epitopes in rheumatoid arthritis also bind citrullinated epitopes and are largely indistinct from anti-citrullinated protein antibodies.

Reed E, Jiang X, Kharlamova N, Ytterberg AJ, Catrina AI, Israelsson L, Mathsson-Alm L, Hansson M, Alfredsson L, Rönnelid J, Lundberg K.

Arthritis Res Ther. 2016 May 4;18(1):96. doi: 10.1186/s13075-016-1001-6

High sodium chloride consumption enhances the effects of smoking but does not interact with SGK1 polymorphisms in the development of ACPA-positive status in patients with RA.

Jiang X, Sundström B, Alfredsson L, Klareskog L, Rantapää-Dahlqvist S, Bengtsson C.

Ann Rheum Dis. 2016 May;75(5):943-6. doi: 10.1136/annrheumdis-2015-209009. Epub 2016 Feb 22. No abstract available.

Antibodies to Porphyromonas gingivalis Indicate Interaction Between Oral Infection, Smoking, and Risk Genes in Rheumatoid Arthritis Etiology.

Kharlamova N, Jiang X, Sherina N, Potempa B, Israelsson L, Quirke AM, Eriksson K, Yucel-Lindberg T, Venables PJ, Potempa J, Alfredsson L, Lundberg K.

Arthritis Rheumatol. 2016 Mar;68(3):604-13. doi: 10.1002/art.39491

An Immunochip-based interaction study of contrasting interaction effects with smoking in ACPA-positive versus ACPA-negative rheumatoid arthritis.

Jiang X, Källberg H, Chen Z, Ärlestig L, Rantapää-Dahlqvist S, Davila S, Klareskog L, Padyukov L, Alfredsson L.

Rheumatology (Oxford). 2016 Jan;55(1):149-55. doi: 10.1093/rheumatology/kev285. Epub 2015 Aug 13.

2015

Occupational exposure to textile dust increases the risk of rheumatoid arthritis: results from a Malaysian population-based case-control study.

Too CL, Muhamad NA, Ilar A, Padyukov L, Alfredsson L, Klareskog L, Murad S, Bengtsson C; MyEIRA Study Group.

Ann Rheum Dis. 2016 Jun;75(6):997-1002. doi: 10.1136/annrheumdis-2015-208278. Epub 2015 Dec 17

Parity influences the severity of ACPA-negative early rheumatoid arthritis: a cohort study based on the Swedish EIRA material.

Pikwer M, Orellana C, Källberg H, Pikwer A, Turesson C, Klareskog L, Alfredsson L, Saevarsdottir S, Bengtsson C.

Arthritis Res Ther. 2015 Dec 12;17:358. doi: 10.1186/s13075-015-0869-x.

Higher education is associated with a better rheumatoid arthritis outcome concerning for pain and function but not disease activity: results from the EIRA cohort and Swedish rheumatology register.

Jiang X, Sandberg ME, Saevarsdottir S, Klareskog L, Alfredsson L, Bengtsson C.

Arthritis Res Ther. 2015 Nov 6;17:317. doi: 10.1186/s13075-015-0836-6.

Risk factors for the rapid increase in risk of acute coronary events in patients with new-onset rheumatoid arthritis: a nested case-control study.

Mantel Ä, Holmqvist M, Nyberg F, Tornling G, Frisell T, Alfredsson L, Askling J.

Arthritis Rheumatol. 2015 Nov;67(11):2845-54. doi: 10.1002/art.39267.

Interactions Between Amino Acid-Defined Major Histocompatibility Complex Class II Variants and Smoking in Seropositive Rheumatoid Arthritis.

Kim K, Jiang X, Cui J, Lu B, Costenbader KH, Sparks JA, Bang SY, Lee HS, Okada Y, Raychaudhuri S, Alfredsson L, Bae SC, Klareskog L, Karlson EW.

Arthritis Rheumatol. 2015 Oct;67(10):2611-23. doi: 10.1002/art.39228.

Associations with smoking and shared epitope differ between IgA- and IgG-class antibodies to cyclic citrullinated peptides in early rheumatoid arthritis.

Svärd A, Skogh T, Alfredsson L, Ilar A, Klareskog L, Bengtsson C, Kastbom A.

Arthritis Rheumatol. 2015 May;67(8):2032-7. doi: 10.1002/art.39170.

Postmenopausal hormone therapy and the risk of rheumatoid arthritis: results from the Swedish EIRA population-based case-control study.

Orellana C, Saevarsdottir S, Klareskog L, Karlson EW, Alfredsson L, Bengtsson C.

Eur J Epidemiol. 2015 May;30(5):449-57. doi: 10.1007/s10654-015-0004-y. Epub 2015 Mar 12.

Recent infections are associated with decreased risk of rheumatoid arthritis: a population-based case-control study.

Sandberg ME, Bengtsson C, Klareskog L, Alfredsson L, Saevarsdottir S.

Ann Rheum Dis. 2015 May;74(5):904-7. doi: 10.1136/annrheumdis-2014-206493. Epub 2015 Feb 5.

To what extent is the familial risk of rheumatoid arthritis explained by established rheumatoid arthritis risk factors?

Jiang X, Frisell T, Askling J, Karlson EW, Klareskog L, Alfredsson L, Källberg H.

Arthritis Rheumatol. 2015 Feb;67(2):352-62. doi: 10.1002/art.38927.

2014

Response to: 'Obesity and comorbidity are independently associated with a failure to achieve remission in patients with established rheumatoid arthritis' by Ellerby et al.

Sandberg ME, Bengtsson C, Källberg H, Wesley A, Klareskog L, Alfredsson L, Saevarsdottir S.

Ann Rheum Dis. 2014 Sep 26. pii: annrheumdis-2014-206369. doi: 10.1136/annrheumdis-2014-206369. [Epub ahead of print] No abstract available.

Non-HLA genes PTPN22, CDK6 and PADI4 are associated with specific autoantibodies in HLA-defined subgroups of rheumatoid arthritis.

Snir O, Gomez-Cabrero D, Montes A, Perez-Pampin E, Gómez-Reino JJ, Seddighzadeh M, Klich KU, Israelsson L, Ding B, Catrina AI, Holmdahl R, Alfredsson L, Klareskog L, Tegnér J, Gonzalez A, Malmström V, Padyukov L.

Arthritis Res Ther. 2014 Aug 20;16(5):414. [Epub ahead of print]

Overweight decreases the chance of achieving good response and low disease activity in early rheumatoid arthritis.

Sandberg ME, Bengtsson C, Källberg H, Wesley A, Klareskog L, Alfredsson L, Saevarsdottir S.

Ann Rheum Dis. 2014 May 12. doi: 10.1136/annrheumdis-2013-205094. [Epub ahead of print]

Anti-CarP antibodies in two large cohorts of patients with rheumatoid arthritis and their relationship to genetic risk factors, cigarette smoking and other autoantibodies.

Jiang X, Trouw LA, van Wesemael TJ, Shi J, Bengtsson C, Källberg H, Malmström V, Israelsson L, Hreggvidsdottir H, Verduijn W, Klareskog L, Alfredsson L, Huizinga TW, Toes RE, Lundberg K, van der Woude D.

Ann Rheum Dis. 2014 Oct;73(10):1761-8. doi: 10.1136/annrheumdis-2013-205109. Epub 2014 May 8.

Smokeless tobacco (moist snuff) use and the risk of developing rheumatoid arthritis: Results from the Swedish Epidemiological Investigation of Rheumatoid Arthritis (EIRA) case-control study.

Jiang X, Alfredsson L, Klareskog L, Bengtsson C.

Arthritis Care Res (Hoboken). 2014 Apr 9. doi: 10.1002/acr.22325. [Epub ahead of print]

Improved performance of epidemiologic and genetic risk models for rheumatoid arthritis serologic phenotypes using family history.

Sparks JA, Chen CY, Jiang X, Askling J, Hiraki LT, Malspeis S, Klareskog L, Alfredsson L, Costenbader KH, Karlson EW.

Ann Rheum Dis. 2014 Apr 30. doi: 10.1136/annrheumdis-2013-205009. [Epub ahead of print]

Patients with regular physical activity before onset of rheumatoid arthritis present with milder disease.

Sandberg ME, Wedrén S, Klareskog L, Lundberg IE, Opava CH, Alfredsson L, Saevarsdottir S.

Ann Rheum Dis. 2014 Aug;73(8):1541-4. doi: 10.1136/annrheumdis-2014-205180. Epub 2014 Mar 18.

Identification of secreted phosphoprotein 1 gene as a new rheumatoid arthritis susceptibility gene.

Gazal S, Sacre K, Allanore Y, Teruel M, Goodall AH; (The CARDIOGENICS consortium), Tohma S, Alfredsson L, Okada Y, Xie G, Constantin A, Balsa A, Kawasaki A, Nicaise P, Amos C, Rodriguez-Rodriguez L, Chioccia G, Boileau C, Zhang J, Vittecoq O, Barnetche T, Gonzalez Gay MA, Furukawa H, Cantagrel A, Le Loët X, Sumida T, Hurtado-Nedelec M, Richez C, Chollet-Martin S, Schaeverbeke T, Combe B, Khoryati L, Coustet B, El-Benna J, Siminovitch K, Plenge R, Padyukov L, Martin J, Tsuchiya N, Dieudé P.

Ann Rheum Dis. 2014 Jan 21. doi: 10.1136/annrheumdis-2013-204581. [Epub ahead of print

2013

Genetic risk scores and number of autoantibodies in patients with rheumatoid arthritis.

Maehlen MT, Olsen IC, Andreassen BK, Viken MK, Jiang X, Alfredsson L, Källberg H, Brynedal B, Kurreeman F, Daha N, Toes R, Zhernakova A, Gutierrez-Achury J, de Bakker PI, Martin J, Teruel M, Gonzalez-Gay MA, Rodríguez-Rodríguez L, Balsa A, Uhlig T, Kvien TK, Lie BA.

Ann Rheum Dis. 2013 Dec 13. doi: 10.1136/annrheumdis-2013-204173. [Epub ahead of print]

Identification of anticitrullinated protein antibody reactivities in a subset of anti-CCP-negative rheumatoid arthritis: association with cigarette smoking and HLA-DRB1 'shared epitope' alleles.

Wagner CA, Sokolove J, Lahey LJ, Bengtsson C, Saevarsdottir S, Alfredsson L, Delanoy M, Lindstrom TM, Walker RP, Bromberg R, Chandra PE, Binder SR, Klareskog L, Robinson WH.

Ann Rheum Dis. 2014 Jan 16. doi: 10.1136/annrheumdis-2013-203915. [Epub ahead of print]

Familial risks and heritability of rheumatoid arthritis: role of rheumatoid factor/anti-citrullinated protein antibody status, number and type of affected relatives, sex, and age.

Frisell T, Holmqvist M, Källberg H, Klareskog L, Alfredsson L, Askling J.

Arthritis Rheum. 2013 Nov;65(11):2773-82. doi: 10.1002/art.38097.

Parity and the risk of developing rheumatoid arthritis: results from the Swedish Epidemiological Investigation of Rheumatoid Arthritis study.

Orellana C, Wedrén S, Källberg H, Holmqvist M, Karlson EW, Alfredsson L, Bengtsson C; EIRA Study Group.

Ann Rheum Dis. 2013 Jul 25. doi: 10.1136/annrheumdis-2013-203567. [Epub ahead of print]

Silica exposure is associated with an increased risk of developing ACPA-positive rheumatoid arthritis in an Asian population: evidence from the Malaysian MyEIRA case-control study.

Yahya A, Bengtsson C, Larsson P, Too CL, Mustafa AN, Abdullah NA, Muhamad NA, Klareskog L, Murad S, Alfredsson L.

Mod Rheumatol. 2013 Apr 25. [Epub ahead of print]

Regional differences regarding risk of developing rheumatoid arthritis in Stockholm County, Sweden: results from the Swedish Epidemiological Investigation of Rheumatoid Arthritis (EIRA) study.

Källberg H, Vieira V, Holmqvist M, Hart JE, Costenbader KH, Bengtsson C, Klareskog L, Karlson EW, Alfredsson L.

Scand J Rheumatol. 2013;42(5):337-43. doi: 10.3109/03009742.2013.769062. Epub 2013 Apr 23.

Cigarette smoking and smoking cessation in relation to risk of rheumatoid arthritis in women.

Di Giuseppe D, Orsini N, Alfredsson L, Askling J, Wolk A.

Arthritis Res Ther. 2013 Apr 22;15(2):R56. [Epub ahead of print]

Multiplex analyses of antibodies against citrullinated peptides in individuals prior to development of rheumatoid arthritis.

Brink M, Hansson M, Mathsson L, Jakobsson PJ, Holmdahl R, Hallmans G, Stenlund H, Rönnelid J, Klareskog L, Rantapää-Dahlqvist S.

Arthritis Rheum. 2013 Apr;65(4):899-910. doi: 10.1002/art.37835.

Association of environmental and genetic factors and gene-environment interactions with risk of developing rheumatoid arthritis.

Karlson EW, Ding B, Keenan BT, Liao K, Costenbader KH, Klareskog L, Alfredsson L, Chibnik LB.

Arthritis Care Res (Hoboken). 2013 Mar 12. doi: 10.1002/acr.22005. [Epub ahead of print]

Ambient air pollution exposures and risk of rheumatoid arthritis in the Nurses' Health Study.

Hart JE, Källberg H, Laden F, Costenbader KH, Yanosky JD, Klareskog L, Alfredsson L, Karlson EW.

Arthritis Care Res (Hoboken). 2013 Feb 11. doi: 10.1002/acr.21975. [Epub ahead of print]

Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis.

Liu Y, Aryee MJ, Padyukov L, Fallin MD, Hesselberg E, Runarsson A, Reinius L, Acevedo N, Taub M, Ronninger M, Shchetynsky K, Scheynius A, Kere J, Alfredsson L, Klareskog L, Ekström TJ, Feinberg AP.

Nat Biotechnol. 2013 Jan 20;31(2):142-7. doi: 10.1038/nbt.2487. Epub 2013 Jan 20.

2012

Rare, low-frequency, and common variants in the protein-coding sequence of biological candidate genes from GWASs contribute to risk of rheumatoid arthritis.

Diogo D, Kurreeman F, Stahl EA, Liao KP, Gupta N, Greenberg JD, Rivas MA, Hickey B, Flannick J, Thomson B, Guiducci C, Ripke S, Adzhubey I, Barton A, Kremer JM, Alfredsson L; Consortium of Rheumatology Researchers of North America; Rheumatoid Arthritis Consortium International, Sunyaev S, Martin J, Zhernakova A, Bowes J, Eyre S, Siminovitch KA, Gregersen PK, Worthington J, Klareskog L, Padyukov L, Raychaudhuri S, Plenge RM.

Am J Hum Genet. 2013 Jan 10;92(1):15-27. doi: 10.1016/j.ajhg.2012.11.012. Epub 2012 Dec 20.

Genome-wide association analysis of anti-TNF drug response in patients with rheumatoid arthritis.

Umicevic Mirkov M, Cui J, Vermeulen SH, Stahl EA, Toonen EJ, Makkinje RR, Lee AT, Huizinga TW, Allaart R, Barton A, Mariette X, Miceli CR, Criswell LA, Tak PP, de Vries N, Saevarsdottir S, Padyukov L, Bridges SL, van Schaardenburg DJ, Jansen TL, Dutmer EA, van de Laar MA, Barrera P, Radstake TR, van Riel PL, Scheffer H, Franke B, Brunner HG, Plenge RM, Gregersen PK, Guchelaar HJ, Coenen MJ.

Ann Rheum Dis. 2012 Dec 11. [Epub ahead of print]

Polymorphisms in peptidylarginine deiminase associate with rheumatoid arthritis in diverse Asian populations: evidence from MyEIRA study and meta-analysis.

Too CL, Murad S, Dhaliwal JS, Larsson P, Jiang X, Ding B, Alfredsson L, Klareskog L, Padyukov L.

Arthritis Res Ther. 2012 Nov 19;14(6):R250. [Epub ahead of print]

High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis.

Eyre S, Bowes J, Diogo D, Lee A, Barton A, Martin P, Zhernakova A, Stahl E, Viatte S, McAllister K, Amos CI, Padyukov L, Toes RE, Huizinga TW, Wijmenga C, Trynka G, Franke L, Westra HJ, Alfredsson L, Hu X, Sandor C, de Bakker PI, Davila S, Khor CC, Heng KK, Andrews R, Edkins S, Hunt SE, Langford C, Symmons D; Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate; Wellcome Trust Case Control Consortium, Concannon P, Onengut-Gumuscu S, Rich SS, Deloukas P, Gonzalez-Gay MA, Rodriguez-Rodriguez L, Ärlsetig L, Martin J, Rantapää-Dahlqvist S, Plenge RM, Raychaudhuri S, Klareskog L, Gregersen PK, Worthington J.

Nat Genet. 2012 Dec;44(12):1336-40. doi: 10.1038/ng.2462. Epub 2012 Nov 11.

Ambient air pollution exposures and risk of rheumatoid arthritis: results from the Swedish EIRA case-control study.

Hart JE, Källberg H, Laden F, Bellander T, Costenbader KH, Holmqvist M, Klareskog L, Alfredsson L, Karlson EW.

Ann Rheum Dis. 2012 Jul 24. [Epub ahead of print]

Long term alcohol intake and risk of rheumatoid arthritis in women: a population based cohort study.

Di Giuseppe D, Alfredsson L, Bottai M, Askling J, Wolk A.

BMJ. 2012 Jul 10;345:e4230. doi: 10.1136/bmj.e4230.

Variants Within STAT Genes Reveal Association with Anticitrullinated Protein Antibody-negative Rheumatoid Arthritis in 2 European Populations.

Seddighzadeh M, Gonzalez A, Ding B, Ferreiro-Iglesias A, Gomez-Reino JJ; Rheumatoid Arthritis Network and Coordinated Project, Klareskog L, Alfredsson L, Dunussi-Joannopoulos K, Clark JD, Padyukov L.

J Rheumatol. 2012 Aug;39(8):1509-16. Epub 2012 Jul 1.

Association between overweight, obesity, ACPA positive and ACPA negative Rheumatoid Arthritis-, results from the EIRA case-control study.

Wesley A, Bengtsson C, Elkan AC, Klareskog L, Alfredsson L, Wedrén S; EIRA study group.

Arthritis Care Res (Hoboken). 2012 Jun 5. doi: 10.1002/acr.21749. [Epub ahead of print]

Genetic and environmental determinants for disease risk in subsets of rheumatoid arthritis defined by the anticitrullinated protein/peptide antibody fine specificity profile.

Lundberg K, Bengtsson C, Kharlamova N, Reed E, Jiang X, Kallberg H, Pollak-Dorocic I, Israelsson L, Kessel C, Padyukov L, Holmdahl R, Alfredsson L, Klareskog L.

Ann Rheum Dis. 2012 Sep 8. [Epub ahead of print]

Occurrence and relative risk of stroke in incident and prevalent contemporary rheumatoid arthritis.

Holmqvist M, Gränsmark E, Mantel A, Alfredsson L, Jacobsson LT, Wallberg-Jonsson S, Askling J.

Ann Rheum Dis. 2012 May 18. [Epub ahead of print]

Smoking interacts with HLA-DRB1 shared epitope in the development of anti-citrullinated protein antibody-positive rheumatoid arthritis: results from the Malaysian Epidemiological Investigation of Rheumatoid Arthritis (MyEIRA).

Too CL, Yahya A, Murad S, Dhaliwal JS, Larsson PT, Muhamad NA, Abdullah NA, Mustafa AN, Klareskog L, Alfredsson L, Padyukov L, Bengtsson C; MyEIRA study group.

Arthritis Res Ther. 2012 Apr 26;14(2):R89. [Epub ahead of print]

Interaction Analysis between HLA-DRB1 Shared Epitope Alleles and MHC Class II Transactivator CIITA Gene with Regard to Risk of Rheumatoid Arthritis.

Ronninger M, Seddighzadeh M, Eike MC, Plant D, Daha NA, Skinningsrud B, Worthington J, Kvien TK, Toes RE, Lie BA, Alfredsson L, Padyukov L.

PLoS One. 2012;7(3):e32861. Epub 2012 Mar 26

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Smoking is associated with an increased risk of developing ACPA-positive but not ACPA-negative rheumatoid arthritis in Asian populations: evidence from the Malaysian MyEIRA case-control study.

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